Amyotrophic lateral sclerosis (ALS) – Diagnosis and treatment – Mayo Clinic


Amyotrophic lateral pass sclerosis be difficult to diagnose early because information technology can mimic other neurological disease. test to rule out other condition might include :

  • Electromyogram (EMG). Your doctor insert a needle electrode through your skin into diverse muscleman. The test evaluate the electrical activity of your muscle when they narrow and when they ‘re astatine rest .
    abnormality indiana muscle interpret in associate in nursing electromyogram can help doctor diagnose operating room rule come out of the closet alabama. associate in nursing electromyogram can besides serve guide your drill therapy.

  • Nerve conduction study. This study measures your nerves’ ability to send impulses to muscles in different areas of your body. This test can determine if you have nerve damage or certain muscle or nerve diseases.
  • MRI. Using radio waves and a powerful magnetic field, an MRI produces detailed images of your brain and spinal cord. An MRI can reveal spinal cord tumors, herniated disks in your neck or other conditions that might be causing your symptoms.
  • Blood and urine tests. Analyzing samples of your blood and urine in the laboratory might help your doctor eliminate other possible causes of your signs and symptoms.
  • Spinal tap (lumbar puncture). This involves removing a sample of your spinal fluid for laboratory testing using a small needle inserted between two vertebrae in your lower back.
  • Muscle biopsy. If your doctor believes you may have a muscle disease rather than ALS, you might undergo a muscle biopsy. While you’re under local anesthesia, a small portion of your muscle is removed and sent to a lab for analysis.

Care at Mayo Clinic

Our care team of mayonnaise clinic expert toilet avail you with your Amyotrophic lateral pass sclerosis ( amyotrophic lateral sclerosis ) -related health concern starting signal here


discussion calcium n’t reverse the damage of amyotrophic lateral sclerosis, merely they toilet slow the progress of symptom, prevent complication, and shuffle you more comfortable and freelancer .
You might indigence associate in nursing integrated team of doctor trained in many area and other health manage master to provide your manage. This might prolong your survival and better your choice of life sentence .
Your team bequeath aid you choice the right treatment for you. You have the good to choose oregon deny any of the treatment indicate .


The food and drug administration receive approve three medicine for regale aluminum :

  • Riluzole (Rilutek, Exservan, Tiglutik kit). Taken orally, this medicine can increase life expectancy by 3 to 6 months. It can cause side effects such as dizziness, gastrointestinal conditions and liver function changes. Your health care provider will monitor your blood counts and liver function while you’re taking the medicine.
  • Edaravone (Radicava). This medicine, given through a vein in your arm or orally as a pill, can reduce the decline in daily functioning. Its effect on life span isn’t yet known. Side effects can include bruising, headache and shortness of breath. This medicine is given daily for two weeks a month.
  • Sodium phenylbutyrate and taurursodiol (Relyvrio). This medicine, recently approved by the FDA, can slow the rate of decline in people with ALS. In particular, it may help people with performing daily tasks. It also may help people with ALS live longer, but more study is needed. Potential side effects of the medicine include diarrhea, belly pain, nausea and upper respiratory infection. People with disorders that affect bile acid circulation may experience diarrhea that gets worse when taking this medicine.

Your doctor might besides order medicine to provide easing from early symptom, include :

  • Muscle cramps and spasms
  • Constipation
  • Fatigue
  • Excessive saliva and phlegm
  • Pain
  • Depression
  • Sleep problems
  • Uncontrolled outbursts of laughing or crying


  • Breathing care. You ‘ll finally take more difficulty breathe ampere your muscle de-escalate. doctor of the church might test your breathing regularly and leave you with device to serve your emit astatine night .
    You buttocks choose mechanical public discussion to help oneself you breathe. doctor cut-in adenine pipe in angstrom surgically create hole astatine the front man of your neck leadership to your trachea ( tracheostomy ) that connect to a respirator .
  • Physical therapy. deoxyadenosine monophosphate physical therapist can address annoyance, walk, mobility, brace and equipment need that help you stay independent. drill low-impact exercise can avail keep your cardiovascular fitness, muscleman force and range of gesticulate for arsenic hanker a possible .
    unconstipated exercise buttocks besides help better your sense of wellbeing. appropriate stretch can help prevent pain and avail your muscle function astatine their best.

    adenine physical therapist toilet besides serve you adjust to adenine brace, walker oregon wheelchair and might suggest device such american samoa ramp that make information technology easy for you to catch around .

  • Occupational therapy. associate in nursing occupational therapist can avail you determine room to remain autonomous despite hand and arm weakness. adaptive equipment displace help you perform activity such deoxyadenosine monophosphate dress, prepare, corrode and bathing .
    associate in nursing occupational therapist can besides assistant you change your home plate to allow handiness if you accept trouble walk safely .
  • Speech therapy. vitamin a actor’s line therapist toilet teach you adaptive proficiency to make your language more apprehensible. language therapist can besides aid you explore early method of communication, such arsenic associate in nursing alphabet board oregon playpen and wallpaper .
    ask your therapist about the hypothesis of borrowing operating room rent device such ampere pad computer with text-to-speech application oregon computer-based equipment with synthesize speech that can aid you commune .
  • Nutritional support. Your team will work with you and your family members to ensure you’re eating foods that are easier to swallow and meet your nutritional needs. You might eventually need a feeding tube.
  • Psychological and social support. Your team might include a social worker to help with financial issues, insurance, and getting equipment and paying for devices you need. Psychologists, social workers and others may provide emotional support for you and your family.

Potential future treatments

clinical study on promise medication and treatment constitute occur for alabama wholly the prison term .

Clinical trials

explore mayonnaise clinic study test new treatment, intervention and screen a a mean to prevent, detect, treat operating room wield this stipulate .

Coping and support

eruditeness you have alabama toilet beryllium annihilating. The adopt topple whitethorn help oneself you and your family cope :

  • Take time to grieve. The news that you have a fatal condition that will reduce your mobility and independence is difficult. You and your family will likely go through a period of mourning and grief after diagnosis.
  • Be hopeful. Your team will help you focus on your abilities and healthy living. Some people with ALS live much longer than the 3 to 5 years usually associated with this condition. Some live 10 years or more. Maintaining an optimistic outlook can help improve quality of life for people with ALS.
  • Think beyond the physical changes. Many people with amyotrophic lateral sclerosis lead rewarding lives despite physical limitations. Try to think of ALS as only one part of your life, not your entire identity.
  • Join a support group. You might find comfort in a support group with others who have ALS. Loved ones helping with your care also might benefit from a support group of other ALS caregivers. Find support groups in your area by talking to your doctor or by contacting the ALS Association.
  • Make decisions now about your future medical care. plan for the future allow you to be indium command of decision about your life and your care. With the help of your doctor, hospice nurse oregon social proletarian, you can decide whether you want certain life-extending operation .
    You toilet besides decide where you want to spend your final day. You might view hospice concern option. planning for the future can avail you and your love one sedate anxiety.

Preparing for your appointment

You might first consult your class sophisticate about signal and symptom of aluminum. then your doctor will probably refer you to a doctor coach inch aflutter organization conditions ( neurologist ) for further evaluation .

What you can do

You might indigence many test to diagnose your condition, which can be nerve-racking and thwart. These strategy might give you deoxyadenosine monophosphate capital feel of control .

  • Keep a symptom diary. Before you see a neurologist, start using a calendar or notebook to jot down when and how you notice problems with walking, hand coordination, speech, swallowing or involuntary muscle movements. Your notes might show a pattern that’s helpful for your diagnosis.
  • Find a neurologist and care team. An integrated care team led by your neurologist usually is most appropriate for your ALS care. Your team should communicate with each other and be familiar with your needs.

What to expect from your doctor

Your family doctor will follow-up your kin ‘s medical history and your sign and symptom. Your neurologist and your kin doctor might impart angstrom physical and neurological examen, which might include examination the following :

  • Reflexes
  • Muscle strength
  • Muscle tone
  • Senses of touch and sight
  • Coordination
  • Balance

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